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From talking robots and video phones to ...

    From talking robots and video phones to rovers (探测器)on Mars, technology has become so advanced that the previously impossible seems to occur on a daily basis. And yetwe still have no cure for the common cold.

Why can't we stop the common cold? According to Peter Barlow, a scientist at Edinburgh Napier University in the UK, the main challenge lies in the many different types of cold viruses that are produced by the rhinoviruses (鼻病毒),Scientific American reported. There are at least 160 types. They mutate so easily that they quickly become resistant to drugs, or learn to hide from our immune systems. In other words, a single cure isn't likely to work on every type of cold.

However, researchers from Stanford University and the University of California, San Francisco, have found a possible answer. They discovered a protein that the viruses need. Without it, they can't spread inside your body.

To identify the gene which produces the specific protein needed by the viruses, researchers used a gene-editing technique to test all genes in the human genome(基因组)one by one for thousands of cell.

These modified (改变的)cells were then exposed to a range of enteroviruses (肠道病毒), including the rhinoviruses which cause the common cold.

All the viruses were unable to replicate(复制)inside cells without a gene that produces a specific protein, called methyltransferase(甲基转移酶)SETD3.

Then, they tested genetically(从基因方面)modified mice, which were completely unable to produce the protein. The mice were able to live healthy, normal lives without the protein.

"Lacking that gene protected the mice completely from viral (病毒的)infection,” associate professor Jan Carette, from Stanford, told the BBC.

"These mice would always die, but they survived and we saw a very strong reduction in viral replication and very strong protection."

Carette said the plan is to find a drug which can temporarily suppress(抑制) the protein, instead of producing genetically modified humans.

“We have identified a fantastic target that all enteroviruses and rhinoviruses require and depend on. Take that away and the virus really has no chance," said Carette.

"This is a really good first stepthe second step is to have a chemical that mimics(模拟) this genetic deletion,” he added.

1.What does the underlined word "mutate” mean in English?

A.To change a new form.

B.To identify a new gene.

C.To check a modified cell.

D.To cure a viral infection.

2.What is the article mainly about?

A.Why it is so hard to cure the common cold.

B.The possible link between rhinoviruses and the common cold.

C.A possible way to stop viral infections that cause the common cold.

D.The functions of a protein needed by viruses.

3.What does Peter Barlow think is the main problem for prevention of the common cold?

A.The slow mutation of some genes.

B.The fast speed at which rhinoviruses spread.

C.The harm rhinoviruses do to the immune system.

D.The wide variety of cold viruses created by rhinoviruses.

4.What can we learn about the protein needed by the viruses?

A.It helps the viruses replicate inside our bodies.

B.It allows the viruses to change easily.

C.It helps the viruses become resistant to drugs.

D.It increases the spread of the viruses.

5.What did the researchers discover in their gene-editing study?

A.Genetically modified mice died because they lacked the protein.

B.The modified cells seemed to protect the mice against viral infections.

C.More methyltransferase SETD3 was produced after the cells were modified.

D.The gene-editing technique was more effective against enteroviruses than rhinoviruses.

6.What do the researchers plan to do next, according to Carette?

A.Conduct experiments on genetically modified humans.

B.Identify a drug that can help reduce the protein.

C.Apply this gene-editing technique to control other viruses.

D.Find a chemical that can cure all enteroviruses and rhinoviruses.

 

1.A 2.C 3.D 4.A 5.B 6.B 【解析】 本文是一篇说明文,介绍了斯坦福大学和旧金山加州大学的研究人员找到了一种可能阻止引起人们感染感冒病毒的方法——抑制一种叫做甲基转移酶SETD3的蛋白质,因为这种蛋白质能够帮助感冒病毒在我们体内复制。 1.词义猜测题。根据画线词后的“they quickly become resistant to drugs, or learn to hide from our immune systems.”可知,它们很快就会对药物产生抗药性,或者学会躲过我们的免疫系统,这说明这些病毒很容易变异,由此可知画线词词义为“变异(变成一种新类型的病毒)”,故A项正确。 2. 3. 4.推理判断题。根据第六段中的“All the viruses were unable to replicate(复制)inside cells without a gene that produces a specific protein, called methyltransferase(甲基转移酶)SETD3.”可知,所有的病毒都不能在细胞内复制,因为它们没有一种基因,这种基因可以产生一种叫做甲基转移酶SETD3的蛋白质,由此可知,病毒所需的蛋白质能够帮助病毒在我们体内复制,故A项正确。 5. 6.推理判断题。根据最后一段“"This is a really good first step—the second step is to have a chemical that mimics(模拟) this genetic deletion,” he added.”可知,“这是一个很好的第一步,第二步是让一种化学物质模拟这种基因缺失”,他(卡雷特)补充说,由此可知,卡雷特认为研究人员下一步打算找出一种能帮助减少这种蛋白质的药物,故B项正确。
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    A decade ago, colored lights danced around the living room on New Year's Eve and happy music was played. Upstairs, the children were asleep. But I wasn't feeling happy. In mid-December, my husband and I had been informed that he had cancer and that he was going to die. He had less than a year left, the doctors said.

In the years since that painful season, I have come to look back upon New Year's Eve as an ending and a beginning. New Year's Eve brings a halt to the endless commitments that fill our daily lives and a chance to reflect.

New Year's Eve is full of possibility, and anticipation. What will be the surprising experiences and delightful successes in the coming year? But also, what disappointments are waiting for us in the next twelve months?

In many ways, New Year's Eve and the days that surround it are a line between past and future. That line is made up of a series of moments of transition that take us out of the old and into the new. Transition can be challenging for many of us. It's about letting go of the familiar and diving headlong (迅猛地)into the unfamiliar.

Just as, back then, I had to face letting go of the life I had led with my beloved husband and stepping into a new world as a widowed(丧偶的)mom. I find that each year I have to step out of the version of me that suited the year that is ending and ease into the version of me who will rise to the goals I am holding for myself for the year ahead.

Last year at this time, I sat in a chair in southern France and drank in the stillness and beauty of the countryside around me. The three children and I had brought into this world talked and laughed around the table beside me as we enjoyed a lunch of bread and cheese.

I was filled with a sense of joy and I had a glowing (热情洋溢的)heart that was full of hope. It was another ending and another beginning. May we all transition into the best of what lies ahead. May we all find happiness in this holiday season.

1.What made the author unhappy on New Year's Eve a decade before?

A.The pressure she faced in her work.

B.The health problem her husband faced.

C.The information received from her family.

D.The relationship between her and husband.

2.What does the underlined word "halt" in Paragraph 2 mean?

A.Stop. B.Beginning. C.Meaning. D.Tradition.

3.What does the author think people should do at a new year?

A.Set challenging goals for the next year.

B.Break with daily routines and form a new habit.

C.Spend more time with family members.

D.Think about the past and get ready for the future.

4.What is the author's attitude toward the future?

A.Calm. B.Indifferent. C.Doubtful. D.Expectant.

5.What is the main purpose of the article?

A.To memorialize her husband.

B.To show how she got through a hard time.

C.To share her view of New Year's Eve.

D.To remind us that uncertainty is part of life.

 

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Headington Oxford

Headington Oxford Summer School is located in the beautiful city of Oxford, just a short walk from the centre. The summer school takes place at Headington School, one of the UK's top boarding schools.

Ages: 13-16

Dates: Wednesday 15 July — Wednesday 19 August

Location: Headington School in Oxford Certification: Academic Progress Report & Certificate

Academic Program

Headington Oxford Summer School offers students 15 hours of English teaching per week. Students can choose between our General English, Summer Study and Global Young Leaders courses. All classes at Headington Oxford Summer School are multi-national with a maximum of 15 students per class.

Social Program

At Headington Oxford Summer School, students enjoy a varied and fun multi-activity program, with a range of activities in the afternoon and evenings. Students can also choose English Plus+ options, to replace the multi-activity program, oil two afternoons per week for an additional cost. Social program is a supplementary(补充)to the Academic Program.

Excellent Education

At Summer Boarding Courses, our English Summer School programs help students to develop and use their English language skills in a real world setting. With students from over 95 different countries, we limit the number of students that speak the same language so that students are able to communicate with each other in English throughout their stay. Trips, project work and presentations throughout our British Summer School courses, help to develop the students' confidence and use of language in real life situations.

A Key Part of the Educational Journey

Joining a British Summer School is part of a student's educational journey. Whether they're attending one of our summer schools to learn English for the first time, develop their English language skills to study in the UK, or intending to prepare for further study at university, we have courses suitable to meet their needs.

CONTACT US MAKE A BOOKING

+44 (0)1943 878518infb@suinmerboardingcourscs.co.uk

1.What do you know about Headington Oxford Summer School?

A.It is far away from the city centre.

B.It offers programs to elementary school students.

C.Its programs are open to students from all over the world.

D.Its programs last no more than 4 weeks.

2.It can be known that the Social Program_______.

A.doesn't include English courses

B.is conducted during the day

C.is an addition to the Academic Program

D.allows students to participate voluntarily

3.Why does the summer school limit the number of students using the same language?

A.To encourage students to make friends.

B.To make students practice English more.

C.To build up students' confidence.

D.To attract more students to the courses.

4.The part "A Key Part of the Educational Journey" ______.

A.further promotes the summer school

B.explains the benefit of joining the summer school

C.explains the development of the summer school

D.predicts the future of the educational area in the UK

 

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    With a combined total of 211 years between them, Charlotte and John Henderson, from Austin, Texas, are celebrating their 80th wedding anniversary. The two are _______ the oldest living couple on earth, according to Guinness World Records. John Henderson is 106 _______ Charlotte Henderson is 105.

The pair met in 1934 as _______ at the University of Texas, where Charlotte was studying to be a teacher and John played football. John was very _______ of football. Since 2010, he has had the _______ of being the oldest living former UT football player, and he _______ a game every year. The Hendersons, who have no children, have _______ at a retirement community in Austin, for the past decade. It is _______ that the retirement home helped to _______ an anniversary party for the couple. “In our ages, we’ve slowed down somewhat,” John Henderson ______________. “We used to go on cruises, but now we have to take it ______________. We like watching sports and talking about what we’re going to do.”

Henderson’s nephew Jason Free said the two were his ______________ role models. They love and really care for each other. “They don’t always ______________ the past,” Free said. “You won’t hear them say, ‘Oh, if only it were 1952 again, ______________ would be great.’ Instead, they are making plans for their ______________ together.”

Free noted that when his uncle is at a UT game or out ______________ friends, Charlotte usually will call to ______________ him. “She likes to know when John is going to be coming back to eat with her,” Free said.

As for the ______________ to their longevity, John Henderson puts it down to exercise and having a positive ______________. Then with a ______________ he added, “But some people think it’s because we’ve never had kids!”

1.A.naturally B.officially C.individually D.normally

2.A.so B.but C.as D.and

3.A.participants B.professors C.students D.players

4.A.fond B.sure C.afraid D.tired

5.A.qualification B.confidence C.truth D.distinction

6.A.organizes B.attends C.sponsors D.appreciates

7.A.aimed B.researched C.lived D.arrived

8.A.reported B.assumed C.suggested D.confirmed

9.A.deliver B.find C.show D.throw

10.A.announced B.recommended C.explained D.complained

11.A.seriously B.easy C.off D.away

12.A.relationship B.behavior C.career D. concept

13.A.overlook B.recall C.believe D.see

14.A.something B.anything C.everything D.nothing

15.A.choices B.children C.retirement D.future

16.A.cheating B.inviting C.meeting D.making

17.A.pick up B.care about C.wait for D.check on

18.A.introduction B.tendency C.secret D.guide

19.A.attitude B.method C.theory D.comment

20.A.laugh B.sigh C.nod D.gesture

 

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We have entered into an age _______ dreams have the best chance of coming true.

A.which B.what C.when D.that

 

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Tom is so independent that he never asks his parents’ opinion ________ he wants their support.

A.since B.once

C.unless D.after

 

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