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His work really ________ in the factory....

His work really ________ in the factory.

A. makes a different    B. makes difference

C. makes different    D. makes a difference

 

D 【解析】 句意:他的工作真的在这个工厂里起了很大的作用。make a difference 意为“有关系,作用,影响”,是一个固定短语,其他三个选项的短语都不成立,故选D。  
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