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He had tried everything but it made litt...

He had tried everything but it made little ____.

A.use

B.good

C.difference

D.result

 

C 【解析】 试题分析:考查固定词组,make little difference意思“没有什么区别”,句子意思“他已经尝试过一切但是没有什么区别” 考点:考查固定词组
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