AIDS may be one of the most undesirable diseases in the world. Luckily, there is now hope for AIDS patients.
According to a recent paper published in the New England Journal of Medicine，Chinese scientists have successfully used CRISPR technology -a method of gene editing-to treat a patient with HIV. While it may not have cured the patient fully, it still represents a huge step forward in fighting the disease.
The patient was a 27-year-old Chinese man who was diagnosed with both AIDS and acute lymphoblastic leukemia (淋巴母细胞白血病), a type of blood cancer. Despite his bleak situation, doctors offered him a little hope: a bone marrow (骨髓) transplant to treat his cancer and an experimental treatment for his HIV. They used this chance to edit the DNA in bone marrow stem cells (干细胞) from a donor before transplanting the cells into the patient.
Specifically, the treatment involved using the gene-editing tool CRISPR-Cas9 to delete a gene known as CCR5, which encodes (给…编码) a protein that HIV uses to get inside human cells. Without the gene, HIV is unable to enter cells. Talking about the gene, lead scientist Deng Hongkui told CNN, “After being edited, the cells and the blood cells they produce have the ability to resist HIV infection.” Nineteen months after the treatment, the patients leukemia was in complete remission( 缓 解 ) and donor cells without CCR5 remained, according to the research paper.
Though the transplant didn't cure the man’s HIV, it still showed the effectiveness of gene-editing technology, as there was no indication of any unintended genetic changes-a major concern with past gene-editing treatment experiments. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security in the United States, who was not involved in the study, praised the treatment. “They did a very creative experiment, and it was safe,” he told Live Science. “It should be viewed as a success.”
Deng believes gene-editing technology could “bring a new dawn” to blood related diseases such as AIDS and sickle-cell anaemia ( 镰 状 细 胞 贫 血 ). “Thanks to this new technology, the goal of a functional cure for AIDS is getting closer and closer,” he said.
1.The underlined word “bleak” in Paragraph3 probably means “______”.
A.hopeless
B.unstable
C.embarrassing
D.unique
2.How did the treatment fight against HIV?
A.By identifying and killing HIV.
B.By changing the structure of HIV.
C.By preventing HIV entering cells.
D.By removing a protein HIV feeds on.
3.What is the result of the treatment?
A.Gene-edited cells are able to resist HIV infection.
B.The number of cells infected by HIV has decreased.
C.CCR5 and other genes in the patient's cells are changed.
D.Unintended genetic changes have taken place in the patient's cells.
4.What can we know about the experiment?
A.It pointed out the problems of gene treatment.
B.It provided a new way to cure AIDS patients fully.
C.It could offer a safe treatment for blood-related diseases.
D.It was the first example to use gene-editing tool to treat AIDS.
Something strange has been happening to me lately: Women in the street have been telling me I'm brave.
My act of courage isn't much-I just stopped coloring my hair. I had brown hair that started going gray when I was 30. So, like a lot of women, I started dyeing (染)it. It was expensive and time-consuming. And my hair grows fast, so I needed to go back to the hair salon(美发厅) every 5 weeks.
Many people seem to enjoy holding onto their youth for as long as possible, giving off the impression that they don' t have much wisdom or many accomplishments. But our hair starts to turn gray and suddenly we start spending $500 or more a year to cover something our male colleagues don’t need to cover.
Of course, People should do what they want with their own body -my mother is 91 and still has "blond" hair, and why not? I just wish more of us would feel that it was OK to be ourselves, because going gray has done more for me than saving me time and money.
I like my natural hair, just as it is. I like how it has got curly and full again. It is recovering after years of being damaged by chemicals. I also like that it has given me some needed attitude in a society that makes youth seem so important, while being against maturity. It reminds me that I'm not a kid anymore - and this isn't a bad thing. Not being a kid anymore means I read the books I want, and not the books i feel I should read. It means not wasting my time at events I don' t need to attend when I’d rather be with my family and friends.
When I see my hair in the mirror, it's a reminder that my time is limited, and I should spend it doing what matters. There's nothing shameful about growing older And pretending it's not happening is a way of giving up our power.
I see my gray hair as a little act of rebellion(反叛)against the idea that people lose value as they age, instead of gaining it. I see gray hair as my "flag" and I'm letting it fly proudly.
1.How does the author feel about coloring hair?
A.It shows people’s great courage.
B.It is a good way to hold onto youth.
C.It shows wisdom and accomplishments.
D.It is not worth the time and money spent on it.
2.What should we do when we grow old according to the author?
A.Give up our power.
B.Pretend to be still young.
C.Accept it and act positively.
D.Read as many books as possible.
3.What is the authors main purpose in writing this passage?
A.To explain why youth is valued.
B.To share her opinion on growing older.
C.To stress the importance of different attitudes.
D.To analyze the advantages and disadvantages of aging.
4.Which can be the best title for the passage?
A.Holding Onto Youth
B.Dyeing Your Hair
C.Gaining Value With Age
D.Valuing Wisdom Of Age
If there was a subject at school that made me anxious, it was science. Maybe that’s because in my tenth grade, I couldn't understand my physics teacher's instructions, causing me to accidentally set fire to the classroom. So, when my husband and I decided to home-school our daughters, we made a deal: he would teach science, while I would handle everything else. But that’s not how things have been going these past few weeks, since my husband has been too busy to teach the girls.
Recently, while out on my morning hike before starting lessons, I noticed that the sky was a beautiful blue, and the air was filled with the sweet smell of flowers. That s why I decided that the day’s lessons would be taught outside, although I remembered that my daughters hadn't had any science classes from my husband for a while.
I returned to the house to get the girls ready. We headed up into the forest, settling ourselves by a pond that rarely has any visitors. My daughter Saoirse started to pick up pond weeds and catch frogs, while my other daughter Ula looked at me, waiting to be instructed. I handed her a drawing board and colored pencils. "We wait, "I told her, " and see if something comes along. In the meantime, just draw what's around you.”
We worked for more than an hour, hardly speaking. A bird flew across the water, and then settled in a front of a fallen tree. I quickly told Ula, worried that she’d not seen the creature. But she had, and she started drawing it. An hour later, she’d not finished her picture and I stared down at it. She drew the bird on her paper with amazing accuracy. But there was one other interesting fact about this drawing: she also drew me, sitting beside her.
I realized, as I stared at this child's drawing of us watching a bird, how I'd lived for 40 years, gathered 10 years of higher education, and never understood the foundation of science before this moment. The foundation of science is a sense of wonder; it isn't about accurately reciting words from a textbook. It is first and foremost about stepping outside our busy lives and amazing at the world around us.
1.How did the author feel about science when in school?
A.She was nervous about it. B.She was fond of it.
C.She was confused about it. D.She was eager for it.
2.The underlined word“it” in Paragraph4 refers to“ ”
A.the fallen tree B.the forest
C.the bird D.the picture
3.Which of the following best describes Ula?
A.She's very outgoing. B.She's good at observing.
C.She's very hard-working. D.She shares interests with her sister.
4.What is the foundation of science in the author's opinion?
A.Attention to accuracy.
B.Curiosity about the outside world.
C.Determination to find out the truth.
D.Ability to understand teachers' instructions.
Looking for work?
Tutors Wanted: Math / Science / Humanities + Test Preparation
Job Posted: 2 days ago
Wage: $27 – 30 per hour
Job Type: Part-time
Schedule: Afternoons, evenings, weekdays, weekends
Job description:
We're looking for tutors to join us before the next school year starts.
Our suitable candidate will be able to assist middle and high school students with test preparation and academic work in Math, Science and / or Humanities.
We'll pay for your training before this fall and can also offer flexible summer tutoring chances, including teaching group classes.
Once our fall semester starts on August 21, we’ll have even higher demand for tutoring sessions on Sundays from 1 p. m. to 8 p.m. as well as from3 p. m. to 9 p. m. Monday-Thursday.
What we offer:
※ Flexible scheduling. Tutors work from 15 to 30 hours per week depending on availability and student demand.
※ Free Sunday dinners during the academic year.
※ Fun staff gatherings
※ Health insurance reimbursement (补偿) for staff working over 30 hours per week.
※ We are 5 minutes’ walking distance from the Menlo Park Caltrain Station.
Applicants must：
※ Have a good command of the subjects they tutor.
※ Be willing to tutor students through the full academic year.
Application instructions:
※ Email us your resume (简历)
※ Tell us why you want to join Academic Trainers and describe your experience of tutoring students if you have any.
※ Let us know your scheduling preferences and potential start date.
※ Tell us which of the subjects you are able to tutor-Math, Science and / or Humanities.
1.Which period of time needs the most tutors during the academic year?
A.Saturday and Sunday mornings.
B.Friday afternoons and evenings.
C.Monday and Thursday mornings.
D.Sunday afternoons and evenings.
2.What can a tutor enjoy who works more than 30 hours per week?
A.Comfortable accommodation.
B.Free job training every month.
C.Health insurance reimbursement.
D.Free meals during the academic year.
3.What qualification should a suitable candidate have?
A.He / She must tutor all the subjects part-time.
B.He / She must be good at the subjects they tutor.
C.He / She must have a previous tutoring experience.
D.He / She must work every evening through the academic year.
请阅读下面内容，并按照要求用英语写一篇150词左右的文章。
P= professor; S=students (In a philosophy class)
P: We all have this one life to live. A fleeting shadow amongst all that exists in this vast universe. We have the ability to accomplish anything, truly anything, if we use our time wisely.
P: (putting some golf balls into the jar) Is this jar full?
S: Yes.
P: (after add some pebbles into the jar) Is it full now?
S: Yes.
P: (after inserting some sand into the jar) How about now, is the jar full now?
S: Yes.
P: Good… (pouring some beer into the jar)
S: … (laughing, smiling, thinking, …)
P: Now I want you to recognize that this jar represents your life. The golf balls are the important things, your family, your friends, your health and your passions. The pebbles are the other important things, your car, your job, your home. The sand is everything else, the small stuff.
P: Now if you put the sand in the jar first you won’t have room for the pebbles or the golf balls. The same is true in life. If you spend all your energy and your time on the small stuff, you won’t have time for all the really important things that matter to you.
P: Pay attention to the things that are critical to your happiness. Take care of the golf balls first. The really important things. Set your priorities. Because everything else is just sand.
S: Professor, what does the beer represent?
P: I’m glad you asked. It goes to show that no matter how full your life may seem to be, there is always room for a couple of beers with a friend.
1. 用约30个词概括上述文中的内容；
2. 谈谈你对文中教授观点的看法，用适当理由或论据支撑你的看法。
3. 就文中所述哲理，谈谈在学习中该怎样践行教授的观点（或你的观点）。
（写作要求）
1. 写作过程中不能直接引用原文语句；2. 作文中不能出现真实姓名和学校名称；
（评分标准）：内容完整，语言规范，语篇连贯，词数适当。
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请阅读下面短文，并根据所读内容在文章后表格中的空格里填入一个最恰当的单词。
“Hey! So, this Lin Daiyu in A Dream of Red Mansions -” The boy elbowed his deskmate, “Why would she hold a funeral for the flowers, and cry while doing so? What was it that made her so sad?”
“You’d wonder, wouldn’t you?” the girl said. And she explained confidently: “What Lin Daiyu did exhibits the qualities and characteristics of literati (文人学士) in ancient China. This was called ‘grieving over spring’s passing and saddened at the arrival of autumn’. That is to say, they tended to express their sentimentality (伤感) in the description of things amidst seasonal changes. This poem you just read, A Sad Song for the Flowers, is a typical work mourning the spring.”
“But spring and autumn are the best seasons. So beautiful! Why would they trigger（引发） these feelings in poets?”
Exactly they do trigger them! The turn of the seasons, at the end of spring or the beginning of autumn often triggered the realization of the elapse of time and the shortness of life. Poets, particularly the lonely, troubled and unfulfilled ones, would describe habitual scenes, such as fallen flowers and running water in spring, or cold wind and cold drizzle in autumn, as symbols of the unavoidable fading of all things vigorous and beautiful. They put into their poems not only the imageries but also their epiphanies（领悟）.”
Seeing the boy was impressed by her eloquence, the girl beamed proudly.
He said, “Well put! I get it now. There are plenty of poems with similar subjects that I have read. Maybe it is common in Chinese classical poetry. But, wait, why is it so? Why were the Chinese poets affected with such a sentiment? Is it limited to Chinese poets?”
“Uh... I wouldn’t say that it is entirely absent from foreign literature, but it is definitely more noticeable in Chinese literature...” flummoxed by the question, the girl was speechless now.
As the two were engaged in their discussion, their Chinese teacher came in. They turned to him for help immediately.
The teacher said, “Behind the strong emotions about spring and autumn is the general sensitivity of the Chinese people to the changes of Nature. I’m sure you both have learned in history class that ancient China was an advanced agricultural civilization, which largely depended on Nature to grow crops and reap the harvest. This in the long run gave the Chinese people a deep sense of awe in the face of Nature, and great sensitivity to the changes of the weather, which triggered their emotions at the turn of seasons.”
“In the case of Daiyu and the ‘flower funeral’, it’s easy to understand in the context of the traditional Chinese concept of the Unity of ‘Man and Nature’, which regards Man as an essential part of Nature. What Daiyu was doing was relating herself to the flowers, and sympathizing with them, which was philosophically and cognitively pre-programmed in the Chinese cultural DNA.”
Title: Grieving Over Spring’s Passing and Saddened at the Arrival of Autumn
Why did Daiyu 1. flowers in a sad mood? | |
1. She related herself to the flowers and 2. with them. | 2. What she did was 3. of literati in ancient China, expressing their sentimentality by 4. things amidst seasonal changes. |
Why would spring and autumn trigger 5. in poets? | |
1. The turn of seasons often 6. ancient people of the passing of time and shortness of life. | 2. Habitual scenes would be used by poets to 7. the disappearing of the past vigor and beauty. |
Why was such a sentiment noticeable in the Chinese poets but8.in foreign literature? | ||
1. Chinese people were generally 9. to the changes of Nature. | 2. Traditional Chinese concept believed Man and Nature were 10., Man as an essential part of Nature. | 3. It was philosophically and cognitively pre-programmed in the Chinese cultural DNA. |
